People

Prof. Simon R. Myers

Our group is based jointly at the Department of Statistics, and the Wellcome Trust Centre for Human Genetics. We are broadly interested in answering questions in statistical, population, and medical genetics. We develop and apply model-based computational techniques, and perform lab-based research. One strong focus of the group’s research is the study of the basic biological process of recombination, and its links to fertility and health in mammals. A second focus is inference of fine-scale population structure – within individual countries – and the genetic impacts of migration events, in humans and other species.

CV - ORCID Profile - myers@stats.ox.ac.uk

Dr Emmanuelle Bitoun

I am a postdoc performing experimental lab-based research to study recombination, and its links to speciation, in mammals. I leverage a variety of experimental techniques including ChIP-Seq, fertility assays, transfection, and the investigation of protein-protein interactions.

Dr Anastasia Ignatieva

I am a postdoc at the Department of Statistics. I am broadly interested in genealogy-based statistical approaches and computational tools for analysing genetic sequencing data, and am currently working on developing scalable methods for understanding aspects of human evolution.

Nikolas Baya

I am a DPhil student co-supervised by Prof. Simon Myers and Prof. Cecilia Lindgren as part of the Genomic Medicine and Statistics programme. In my research I study the genetic architecture of extreme and unexpected phenotypes. I received an undergraduate degree in applied mathematics at Brown University and worked at the Broad Institute of MIT and Harvard before coming to Oxford.

Jessica Cho

I am an undergraduate student in Biomedical Sciences, gaining more lab experiences through my placement year here with the Myers group.

Lino Ferreira

I am a DPhil student in the Genomic Medicine and Statistics programme. My research focuses on the portability of GWAS associations and polygenic risk score performance across populations. Prior to starting my DPhil, I completed an MSc in statistics at the University of Edinburgh.

Dr Christopher C. Gill

I am working with the ancestry company LivingDNA. This is part of the Systems Approaches to Biomedical Sciences (SABS) doctoral program. I am currently interested in developing statistical tools and pipelines to provide new insights into genetic ancestry estimation.

Having completed my degree in 2006, covering a wide range of mathematical topics, I went on to complete a DPhil, focussing on the representation theory of finite groups. Much of my time was spent studying questions related to the decomposition numbers. More specifically, I studied properties of Young modules, an important aspect of the representation theory of the symmetric group, and more generally trivial source modules for finite groups. I spent several years pursuing research in this area, whilst enjoying a considerable amount of teaching. I held positions at Charles University in Prague, and at Somerville College and Keble College in Oxford. In 2015 I decided to pursue a more interdisciplinary approach to research in the biological/biomedical setting.

Yunong Lin

I am a DPhil student co-supervised by Prof. Simon Myers and Prof. Robert Davies. I am currently working on the GWAS associations of stratified cohorts. I did my MSc in statistics at University of Wisconsin-Madison, and worked as a research specialist there for a year after my graduation.

Hrushikesh Loya

I am a DPhil student in Genomic Medicine and Statistics jointly co-supervised by Prof. Simon Myers and Prof. Pier Palamara. My primary research interest involves Bayesian method development for application in statistical and population genetics. Before Oxford, I completed my bachelor’s and masters in electrical engineering from IIT Bombay, India.

Brynelle Myers

I am a lab-based experimental researcher in Simon Myers’ team since September 2021. I am currently working on mammalian meiosis, including epigenetic regulation of gene expression using single-cell technologies. I obtained my MPhil degree at Newcastle University prior to working at the University of Cambridge (2017-2019) and Wellcome Sanger Institute (2019-2021).

Sinan Shi

I am a DPhil student co-supervised by Prof. Simon Myers and Prof. Pier Palamara, working on the phasing and imputation of 100,000 Genomes Project of Genomics England. Previously, I worked as a research software engineer in various research institutes.

Miriam Stricker

I am a DPhil student co-supervised by Prof. Pier Palamara (Systems Approaches to Biomedical Sciences CDT, collaboration with Satu Nahkuri, Roche). My current research is focused on developing machine learning algorithms to study how variation in non-coding parts of the genome influences the epigenetics and expression levels of coding parts of the genome, with applications within cancer immunotherapies. Before joining the lab I worked in Biophysics and obtained degrees from Heidelberg University.

Luis Torada Aguilella

I am a DPhil student co-supervised by Robert Davies and Simon Myers at Oxford, as well as Satu Nahkuri and Tony Kam-Thong at Roche. I am currently investigating genetic heterogeneity within Autism Spectrum Disorder. Before coming to Oxford, I did a BSc in Biochemistry at University of Navarra (Spain) and a MSc in Bioinformatics and Systems Biology at Imperial College London (UK). I then joined the Systems Approaches to Biomedical Science Doctoral Training Center (SABS DTC) at Oxford, starting my DPhil in Nov 2019. My current project reflects my major research interest: large-scale dataset modelling with health impact.



Alumni

Post-doctoral researchers

Dr Leo Speidel

Dr Leo Speidel completed a DPhil (link to thesis) and postdoc (2016-2020) working on a method for estimating genealogies for thousands of DNA samples. The method, Relate, is available at https://myersgroup.github.io/relate/. He is now a Sir Henry Wellcome fellow at UCL, Genetics Institute and the Francis Crick Institute in London.

Dr Sile Hu

Dr Sile Hu completed a postdoc working on the project Building a platform for genetic inference from the Genomics England data. He is now a Research Scientist at the Novo Nordisk Research Centre in Oxford.

Dr Ran Li

Dr Ran Li completed a postdoc working on the resolution of recombination. She is now a postdoctoral researcher in the Peter Ratcliffe Group in Oxford.

Previous post-doctoral alumni


Research students

Dr Daniel Wells

Dr Daniel Wells completed a DPhil (2015-2019) investigating patterns of gene expression in meiosis (link to thesis). He is now a Precision Health Scientist at Genomics plc.

Dr Clare Bycroft

Dr Clare Bycroft completed a DPhil (2013-2017) on the inference of demographic history from patterns of genetic variation (link to thesis). She is now a Scientist at Genomics plc.

Previous student alumni